One of the less charming traditions of the UK meat industry has been to force herbivores to cannibalise the remains of their butchered companions. The consequences have been gruesome for animals and people alike. By promoting enforced cannibalism, UK agribusiness and the meat trade have unleashed the human analogue of bovine spongiform encephalopathy on the population at large.
Prion-based diseases have long incubation periods. These may extend two decades or more. The likely toll of future human victims of Creutzfeldt-Jacob Disease (CJD), the human variant
of BSE, is unknown.
Bovine Spongiform Encephalopathy (BSE) has been dubbed "Mad Cow Disease". This is because of
the signs of extreme distress and disordered gait which its victims display before death. BSE is a
neuro-degenerative disease of cattle. BSE is invariably fatal. Its immediate cause lies in mysterious infectious proteins called prions.
Prions behave as infectious agents. Yet they
are 100 times smaller than viruses. Their mechanism of replication is still unclear. All the prion diseases - new-variant-CJD is only the most notorious - are associated with the accumulation in the brain of an abnormal and protease-resistant isoform of
the prion protein, PrP.
The British outbreak of BSE struck down around 160,000 cows in 1980s and 1990s. Long before conclusive proof became available, strong circumstantial evidence pointed to the macabre cost-saving practice of mixing the remains of sheep - including
brains and bones - into cows' feed as the cause of the deadly syndrome.
